Hereditary multiple exostoses (HME), also called hereditary multiple osteochondromas, is a rare genetic disorder characterized by multiple osteochondromas that grow near the growth plates of bones such as the ribs, pelvis, vertebrae and especially long

Hereditary multiple exostoses (HME) is an inherited genetic condition characterized by the presence of multiple exostoses (osteochondromas). MHE is a relatively rare autosomal dominant disorder, mainly caused by loss of function mutations in two genes:

Multiple Hereditary Exostoses (MHE) is a rare, pediatric, autosomal dominant musculoskeletal disorder that affects about 1 in 50,000 children worldwide (1, 2). MHE, also known as Hereditary Multiple Exostoses (HME) or Multiple Osteochondromas (MO),